The IBM Clinical Genomics for targeted clinical research

THe Haifa Lab of IBM provides the Technlogy for Clinicalgenomics and leads the research in lifesciences fieds.

The Clinica, Genomics division plans to provide technology to integrate clinial genomics data and HL7 and other complaince protocls followed in clinical research and clinia, trial and integrate them to provide better and focused clinical trials

Clinical genomics for biopharmaceuticals from IBM

the main advatages as per IBM website is that

  • Encapsulate raw genomic data into an HL7 Clinical Genomics message, including transformation services of proprietary data formats to standardized formats like MAGE and BSML
  • Access patient’s clinical history stored in an enterprise EHR system
  • Access all major ontologies that provide genotype-phenotype relationships like OMIM, PharmGKB, etc.
  • Parse the encapsulated raw genomic data and bubble-up selected genomic data items based on ontological knowledge as well as the patient clinical data
  • Compare two Genotypes (the data model at the heart of the HL7 specs) in order to provide case-based reasoning services to decision support application that will use CGL7 as a specialized clinical genomics middleware
  • Find a similar pedigree in case base of pedigrees in order to support risk assessment applications that base their assessment on family history
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Hocus Locus Spins out of University of Albany

Hocus Locus, a bioinformatics company which is part of the $225 million Gen*NY*Sis   Programe (Generating Employment through New York State Science) is located at the Center for Excellence in Cancer Genomics in University of Albany, it makes products to help small drug discovery companies speed up development of new drugs.

Plants too recognise its kin

Now wonder,  research proves that even plants recognise their kins. Researchers from McMaster University have found that plants go competitive when forced to share their own environment like pot, with strangers of the same species, but they’re accommodating when potted with their siblings.

How they do it???

When a different plant of same species is potted with a growing plant they start growing more roots, which allows them to grab water and mineral nutrients before their neighbours get them. when they share a pot with family i.e the sibiling 1st or 2 nd generation they don’t increase their root growth. Because differences between groups of strangers and groups of siblings only occurred when they shared a pot, the root interactions may provide a cue for kin recognition. The following is the paper that is being published on the same.

Dudley, S. A. and A. L. File (2007). Kin recognition in an annual plant. Biology Letters, in press.

4th Dimension in Biology

4D imaging of different microorganisms was the first step of 4D in biology. Recently now from the University of Calgary, sun centre for excellence for visual genomics have created the 4D virtual human (CAVEman) with flesh, and muscles, a breakthrough step ahead in the medical informatics. This 4D virtual human can be used for many new pathways for surgical studies. It can be used also to see the disease and genetic changes virtually, allowing to assess the various morphological changes occuring during a diseased or genetically affected individual. You can download Demo verrsion so of the 4D demos of heart , human skelton and many more,

Future of High Throughput Genome Sequencing

In Bangalore Bio 2007 LabIndia has introduced  SOLiD: Sequencing by Oligonucleotide Ligation and Detection which is the Future of High Throughput Sequencing.

“This is useful for those who want to do full genome sequencing. Whole genome projects will be more cost effective with this new instrument than they are today,” said Dr. Anupama Gaur, Team Leader Application Support, Labindia Instruments, Pvt. Ltd.

HistoGenetics has come up with Sequence Based Typing which has many advantages such as identifying many rare and new alleles. “Nearly 2000 alleles have been identified so far and it has been launched in the US and UK as of now” said Dr. Cereb Nezih, M.D., President and co-founder, Histogenetics, Inc.

State law protects DNA of Minnesota wild rice

ST. PAUL — The DNA of Minnesota wild rice gets special protection under a new state law adopted this year with the backing of Indian tribes.

Genetic modifications to wild rice will be watched more closely, with environmental impact statements required and permits controlled by the Minnesota Environmental Quality Board.

Stein GAVE Bioinformatics Ten Years to Live

Its an old story but looking at whats happening in bioinformatics industry now i think this topics some what relevant. The industry has seen an unprecedented number of mergers and collaboration something unthinkable at the early stages of bioinformatics era.

Lincoln Stein’s keynote at the O’Reilly Bioinformatics Technology Conference was provocatively titled “Bioinformatics: Gone in 2012. it was proved to some level that all the compaies that sproute up are not going to be around for a long time. but it seems 2012 is defenitely not going to be the end of bioinformatics. personalized medicine, functional genomics and theranostics have given it a new lease of life and lot of steam to speed ahead

the old article is present at oreilynetwork 

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