Entire Genome Sequencing from Single Molecule DNA

Cambridge based Helicos Bioscience announced the publication of a report in Science Magazine demonstrating the first single molecule sequencing of an organism (M13 virus genome) examining more than 280,000 strands of captured DNA.

Helicos’ uses a proprietary form of sequencing-by-synthesis called True Single Molecule Sequencing(tSMS)™. Unlike other methods, the technique builds up the sequence of each strand of DNA one base at a time.

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2 Responses

  1. Whole Genome tSMS is here…and single molecule sequencing will replace most other sequencing technologies by 2010. There is no doubt of that

    -Steve
    http://www.thegenesherpa.blogspot.com

  2. wow… nice info.., stil can’t belive it,…
    the techonology it’s advancing so fast…

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