ENCODE consortium: forming background of why 3 billions bp are required for a human to survive not just the set of genes.

ENCODE consortium today published one in nature and 28 papers in genome research involving 35 groups from 80 organizations around the world, which promise to reshape our understanding of how the human genome functions. The findings totally challenge the tidy collection of independent genes , but sees as a complex networking system, along with regulatory elements and other types of DNA sequences that do not code for proteins, interact in overlapping ways not yet fully understood.

“This impressive effort has uncovered many exciting surprises and blazed the way for future efforts to explore the functional landscape of the entire human genome,” said NHGRI Director Francis S. Collins, M.D., Ph.D. “Because of the hard work and keen insights of the ENCODE consortium, the scientific community will need to rethink some long-held views about what genes are and what they do, as well as how the genome’s functional elements have evolved. This could have significant implications for efforts to identify the DNA sequences involved in many human diseases.”

Loads to come out of this …. few days back in nature cell biology there was a article stating small peptide regulators of actin-based cell morphogenesis encoded by a polycistronic mRNA in an eukaryote…

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2 Responses

  1. […] ENCODE consortium today published one in nature and 28 papers in genome research involving 35 groups from 80 organizations around the world, which promise to reshape our understanding of how the… …more […]

  2. Thanks for the news alert! This is an important research result and especially relevant for me since I routinely do multiple species alignments to analyze gene networks.

    You have a really informative blog. I write a science blog called Fresh Brainz mainly about evolutionary biology and some neuroscience.

    Would you like to exchange blog links?

    Best regards!

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