AstraZeneca Announce Real-World Evidence Data Collaboration

AstraZeneca Pharmaceuticals LP (NYSE: AZN) and HealthCore, Inc., the health outcomes research subsidiary of WellPoint, Inc. (NYSE: WLP), announced a collaborative agreement to conduct real-world studies designed to determine how to most effectively and economically treat disease Unlike controlled clinical trials, real-world evidence studies use observational data such as electronic medical records, claims information and [...]

How to improve R&D productivity: the pharmaceutical industry’s grand challenge

   

personalized medicine might be making drug development more complicated

According to a new report from the Tufts Center for the Study of Drug Development at Tufts University 12 to 50 percent of the drugs companies are developing, depending on the company, involved a personalized medicine approach. The Tufts report is based on a survey of 25 companies, large and small, to which 16 companies [...]

Oracle starts the Oracle Health Sciences Institute (OHSI), in partnership with Sun Labs

The Institute is focused on research that will accelerate IT innovation to advance personalized medicine and the delivery of safe and effective   treatments and health care services to patients around the globe. OHSI will work in tandem with academic research centers, focusing on a targeted set of research areas fundamental to the R&D and [...]

CombiMatrix Molecular Diagnostics Launches Microarray Test for Detection of Autism Spectrum Disorder

CombiMatrix  has completed the clinical validation of the  BAC array CGH based clinical microarray tests. ATScan is designed to detect known genomic copy-number variations  associated with Autism Spectrum Disorder and this test is now available to physicians and consumers.

So Thats how Humans Evolved! – Now we can begin to answer the big question

Which of the thousands of long stretches of repeated DNA in the human genome came first? And which are the duplicates the question have been answered by a team of scientists from University of Washington School of Medicine and University of California, San Diego.The research published by Evan Eichler from the University of Washington School [...]

Gene Logic sells in genomics division

It hardly a week I have wrote about acquisition and mergers , it seems the rain is noit going to stop any time soon, the latest one , to give away the home plate is Genelogic agreeing to sell its genomics division to India HQ Ocimum Biosolutions subject to the authorization of the transaction at [...]

Oracle Openworld 2007- Personalized Genomics session

Its the time -Personalized Genomics Advances in genetic information and laboratory technologies mean new ways to diagnose disease and determine patient risk. The wealth of genetic information makes it harder to provide meaningful information. During Oracle OpenWorld 2007 Oracle is presenting how laboratory information systems principles and Oracle customer relationship management and enterprise resource planning [...]

Transplant Patients Could Live Free of Anti-Rejection Drugs

Scientists from the Lucile Packard Children’s Hospital and the Stanford University School of Medicine have identified a pattern of gene expression shared by a small group of patients who beat the odds and remained healthy for years without medication, after undergoing Organ transplant. The findings made by Minnie Sarwal, MD, PhD, a pediatric nephrologist at [...]

The IBM Clinical Genomics for targeted clinical research

THe Haifa Lab of IBM provides the Technlogy for Clinicalgenomics and leads the research in lifesciences fieds. The Clinica, Genomics division plans to provide technology to integrate clinial genomics data and HL7 and other complaince protocls followed in clinical research and clinia, trial and integrate them to provide better and focused clinical trials Clinical genomics [...]

Pharmacogenomics has started

IT been a long time since my last post, So I thought of catching up with other blogger before going to do anything myslef. So here is what got my attention from Alla Katsnelson blog on the scientist magazine  that  USFDA approved updated labeling for the widely used blood-thinning drug, Coumadin, to explain that people’s [...]

Affymetrix expands into personalized medicine The next big thing

Affymetrix expands into personalized medicine! Why because The next big thing in health care? is You the individual personalized medicine is the place step every one wants to be. Roche recently went after Nimblegen for a small foothold in this developing ssicne field, Now its the turn of Affymetrix the leader in microarray DNA chips. [...]

Microarray to detect mutations in largest Human Gene

The average human gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. Residing at Chromosome 4 it has long been of interest to the medical community because its the gene responsible for huntington’s disease, polycystic kidney disease, a form of muscular dystrophy and [...]

Indian genetic database offers R&D advances

Imagine a diabetic patient from NewYork being put on a drug regimen distinct from a patient London. Personalized medicine allows tratement to decided on the genetic make up of the individual. Genetically europeans and asians and others have different ways of responding to same treatment genetically FortunatelyIf Indian researchers have their way, such customised medication [...]

UK is appealing for volunteers to help worlds biggest medical experiment project- to understand impact of Genetics and life style in illness and medical treatment

 UK is appealing for volunteers to help worlds biggest medical experiment project- to understand impact of Genetics and lifestyle in health and medical treatment The  BBC reports about a medical experiment aiming to be the biggest in the world is appealing for volunteers to help end Scotland’s reputation as the “sick man of Europe”. The [...]

12 DNA tests that Could Change Your Life-selected by Forbes

The complete list is published at forbes website Breast Cancer Adult-Onset Diabetes Obesity Drug Metabolism Crohn’s Disease Prostate Cancer Duchenne Muscular Dystrophy Rett Syndrome Macular Degeneration Alzheimer’s Disease Heart Attack Gene Testing: Related Blogs eyeondna , gensherpa , OmicsOmics

ASGT unveils new Platform for Regulating Expression of therapeutic Genes

During 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle a new methid for  Regulating Expression of therapeutic Genes was introduced. For many applications, gene transfer is being employed to engineer cells for therapeutic applications, chek the following links for article 1 IFR , 2 (Nature), 3 (NIH) , that require [...]

Genes add up risk of autoimmune disease

Geneticists have identified a link between the number of copies of a specific gene an individual has and their susceptibility to autoimmune diseases like lupus. The research by Professor Tim Aitman of the Medical Research Council Clinical Sciences Centre at Imperial College London, and colleagues, is published in Nature Genetics. From Medical News 

Microarray based DRUG DISCOVERY and CLINICAL DIAGNOSIS and biosensor designed to identify viruses

 Prof. David Dandy of Colorado State University chemical and biological engineering has proven that called microarray assays can be used for biomedical disease and drug screening assays could rapidly increase drug discovery, Although not ready for hospital or office use, microarrays represent a novel miniaturized multi-spot diagnostic format that has huge potential for patient diagnosis [...]

‘Personalized Medicine’ Goal of Human Genetics Initiative

Oregon Health & Science University effort, launched 25-April 2007 during National DNA Day, will meld genetics and clinical care OHSU today is launching the Human Genetics Initiative (HGI), an effort that brings together the university’s vast array of genetics research resources and brainpower, and applies them in a health care setting. It will allow the [...]