The Staphylococcus aureus microarray Database inching closer to Staph Infection Vaccine

MRSA the very name send shudders to any one working in a hospital setup, the aggressive Methicillin-resistant Staphylococcus aureus (MRSA) , is a bacterium responsible for some difficult-to-treat infections in humans. The organism is often the cause of community-acquired MRSA (CA-MRSA) or hospital-acquired MRSA (HA-MRSA) depending upon the circumstances of acquiring disease, University of Southern [...]

New Microarray technology replacing PCR and speed up HTS

Dr. Richard Gibbs, director of the Baylor College of Medicine Human Genome Sequencing Centre and his researchers along with the help of  NimbleGen Systems the  company recently acquired by Roche Applied Science has developed a new technique that combines gene chip technology with the latest generation of gene sequencing machines to allow fast and accurate sequencing of selected [...]

Transposon insertion site profiling chip (TIP-chip)

Transposon insertion site profiling chip (TIP-chip) was invented by Researchers at the Johns Hopkins’ High Throughput Biology Center. Tip-chip can be used to help identify otherwise elusive disease-causing mutations in the 97 percent of the genome long believed to be “junk.” TIP-chip (transposable element insertion point) can locate in the genome where so-called jumping genes [...]

Microarrays in daily life

Accurate assessment of a calf’s future performance may soon be possible by using microarrays. By 2010, less than three years away, Australia’s largest integrated beef research program, the Beef Cooperative Research Centre (CRC) anticipates cattle breeders may be able to get an accurate assessment of a bull or a dam’s future performance within a few [...]

Microarray based DRUG DISCOVERY and CLINICAL DIAGNOSIS and biosensor designed to identify viruses

 Prof. David Dandy of Colorado State University chemical and biological engineering has proven that called microarray assays can be used for biomedical disease and drug screening assays could rapidly increase drug discovery, Although not ready for hospital or office use, microarrays represent a novel miniaturized multi-spot diagnostic format that has huge potential for patient diagnosis [...]

Scared of GMO and GM food

 Detecting Genetically Modified Organisms with Microarrays Is Genetically modified Food a health Hazard ? according to many it seems so. European union has always taken a stringent rules against GM food. A microarray was developed for detecting the presence of Genetically modified organisms some time back a pdf of the article can be downlaoded from [...]

Whole Genome microarray @ 99 USD

Ocimum Biosolutions is offering whole genome microarrays at 99 USD as part of its 6th year celebration, The limited period marketing offer is available for many cataloge whole genome microarrays at 99 USD.  irrespective of the number of microarrays ordered. The company now offers one of the best cost effective microarray prices in the market [...]

Microarray based Bio Detection Technologies

DNA microarray detection of antimicrobial resistance genes in diverse bacteria Study published at http://cat.inist.fr/?aModele=afficheN&cpsidt=17459830 High throughput genotyping is essential for studying the spread of multiple antimicrobial resistance. A test oligonucleotide microarray designed to detect 94 antimicrobial resistance genes was constructed and successfully used to identify antimicrobial resistance genes in control strains. The microarray was then [...]

Genetically Guided Treatment For Cancer

Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Researchers developed and validated a new genomic microarray test that identifies whether a [...]

New non-parametric analyis algorithm for Detecting Differentially Expressed Genes with Replicated Microarray Data

Previous nonparametric statistical methods on constructing the test and null statistics require having at least 4 arrays under each condition. In this paper, we provide an improved method of constructing the test and null statistics which only requires 2 arrays under one condition if the number of arrays under the other condition is at least [...]

Even the hopeful US president jumps on Web2.0 bandwagon

 Barack Obama looks to be diving into this whole “Web 2.0″ thing head first, what with his own Facebook profile, Flickr account, and YouTube account. In addition to all this stuff, he also has my.barackobama.com, a social networking type site for his supporters to create profiles, network, and make blogs all about how great Barack [...]

A new twist on DNA-dynamic quality of epigenetics

What makes you different from everyone else on the planet may have less to do with the spelling of your genetic code than with a scattering of chemical “tags” that, like censor’s marks, render some of your genes unreadable.The code itself, after all, is 99.9 percent identical in all of us, so these peripheral elements [...]

Microarray for Catharanthus Roseus

In the recently concluded Bio-Asia 2007 meeting  Ocimum Biosolutions has entered into an accord with a scientist for developing microarray  on the medicinal plant Catheranthus Roseus.    Catharanthus roseus is known as the common or Madagascar periwinkle, though its name and classification may be contradictory in some literature because this plant was formerly classified as [...]

NYIT Professor Discovers Next Generation of DNA and RNA Microarrays brings hopes of personalized medicine

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer’s, diabetes, and genetic and infectious diseases. The invention allows the immobilisation of intact. double-stranded, multi-stranded or alternative DNA or RNA and has the potential to revolutionise [...]

Microarray test to anlyse the role of estrogen in breast cancer

Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Researchers developed and validated a new genomic microarray test that identifies whether a [...]

Usage of Low-Density Oligonucleotide Microarrays for Prognosis Prediction of Colorectal Cancer Patients

Colorectal cancer (CRC) is one of the most common malignancies. Unfortunately a significant proportion of surgically cured patients in the early stage of the disease develop progression and die from the disease. DNA microarrays technology was used in more than sixty studies focused on colorectal cancer during last five years. High-density DNA microarrays showed good [...]

Scientists find Extraterrestrial genes in Human DNA

A group of researchers working at the Human Genome Project indicate that they made an astonishing scientific discovery: They believe so-called 97% non-coding sequences in human DNA is no less than genetic code of extraterrestrial life forms. The non-coding sequences are common to all living organisms on Earth, from moulds to fish to humans. In [...]

Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis: a cohort study

source : http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1555602   Postmenopausal hormone-replacement therapy (HRT) increases breast-cancer risk. The influence of HRT on the biology of the primary tumor, however, is not well understood.   We obtained breast-cancer gene expression profiles using Affymetrix human genome U133A arrays. We examined the relationship between HRT-regulated gene profiles, tumor characteristics, and recurrence-free survival in 72 [...]

DNA microarray–based analysis may be useful for assessing the risks and benefits of hormone therapy

Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis. The US FDa has apprved use of two new microarrays for clinical decision making. The US Food and Drug Administration (FDA) encourages the development of new technologies such as microarrays which may improve and streamline assessments of safety and the effectiveness of medical [...]

microarray for transgenomics studies and Study of Evolution of organisms

Barcode microarrayshas demosntrated the various ways in which the microarrays can be used in various ways.Though mirred in controvesy as any new technology has been subjected in its infancy, the basic principles behind the technology can be put to use in many other frontiers. It may be optimized to study transgenomics organims and its evolution. [...]