CombiMatrix Molecular Diagnostics Launches Microarray Test for Detection of Autism Spectrum Disorder

CombiMatrix  has completed the clinical validation of the  BAC array CGH based clinical microarray tests. ATScan is designed to detect known genomic copy-number variations  associated with Autism Spectrum Disorder and this test is now available to physicians and consumers.

Microarray based DRUG DISCOVERY and CLINICAL DIAGNOSIS and biosensor designed to identify viruses

 Prof. David Dandy of Colorado State University chemical and biological engineering has proven that called microarray assays can be used for biomedical disease and drug screening assays could rapidly increase drug discovery, Although not ready for hospital or office use, microarrays represent a novel miniaturized multi-spot diagnostic format that has huge potential for patient diagnosis [...]

Theranostics-Genetics Testing for Clinical Diagnostics for Personalized Medicine

Theranostics is the term used to describe the proposed process of diagnostic therapy for individual patients – to test them for possible reaction to taking a new medication and to tailor a treatment for them based on the test results or in plain english Personalized Medicine. Personalized medicine is the use of detailed information about [...]

Microarray based Bio Detection Technologies

DNA microarray detection of antimicrobial resistance genes in diverse bacteria Study published at http://cat.inist.fr/?aModele=afficheN&cpsidt=17459830 High throughput genotyping is essential for studying the spread of multiple antimicrobial resistance. A test oligonucleotide microarray designed to detect 94 antimicrobial resistance genes was constructed and successfully used to identify antimicrobial resistance genes in control strains. The microarray was then [...]

Genetically Guided Treatment For Cancer

Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Researchers developed and validated a new genomic microarray test that identifies whether a [...]

New non-parametric analyis algorithm for Detecting Differentially Expressed Genes with Replicated Microarray Data

Previous nonparametric statistical methods on constructing the test and null statistics require having at least 4 arrays under each condition. In this paper, we provide an improved method of constructing the test and null statistics which only requires 2 arrays under one condition if the number of arrays under the other condition is at least [...]

NYIT Professor Discovers Next Generation of DNA and RNA Microarrays brings hopes of personalized medicine

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer’s, diabetes, and genetic and infectious diseases. The invention allows the immobilisation of intact. double-stranded, multi-stranded or alternative DNA or RNA and has the potential to revolutionise [...]

The genetic detective – Pharmacogenomics and personalized medicine

 THe following interesting study was published at  article is from royal society of chemistry website A selective way to detect genetic variations could help scientists develop personalised medicine. “[This method] should allow several thousands of single nucleotide variations, at different positions within a person’s genome, to be analysed in parallel.”- Andreas Marx Variations in our genetic [...]

Indian scientists from CCMB find new genetic mutations- and wins award from UK

UK award for CCMB scientist The Hindu Business Line:January 22, 2007 Hyderabad: Dr K. Thangaraj, a scientist at the Centre for Cellular and Molecular Biology (CCMB), Hyderabad has received the first Major UK-India Education and Research Initiative (UKIERI) Award.Launched by the UK Prime Minister, Mr Tony Blair, during his last visit to India, the UKIERI [...]

Microarray for clinical diagnostics in hand-foot-and-mouth disease

The following study was published in journal of clinical microbiology, Combining Multiplex Reverse Transcription-PCR and a Diagnostic Microarray To Detect and Differentiate Enterovirus 71 and Coxsackievirus A16 Tsan-Chi Chen,1,2 Guang-Wu Chen,3 Chao Agnes Hsiung,4 Jyh-Yuan Yang,5 Shin-Ru Shih,6 Yiu-Kay Lai,2 and Jyh-Lyh Juang1* Division of Molecular and Genomic Medicine, National Health Research Institutes, Miaoli, Taiwan,1 [...]

Usage of Low-Density Oligonucleotide Microarrays for Prognosis Prediction of Colorectal Cancer Patients

Colorectal cancer (CRC) is one of the most common malignancies. Unfortunately a significant proportion of surgically cured patients in the early stage of the disease develop progression and die from the disease. DNA microarrays technology was used in more than sixty studies focused on colorectal cancer during last five years. High-density DNA microarrays showed good [...]

Rapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) using OLigonucleotide microarrays

Published by  1Institute for Medical Microbiology and Hygiene, Faculty of Medicine ‘Carl Gustav Carus’, Technical University of Dresden, Dresden and 2Clondiag Chip Technologies GmbH, Jena, Germany ABSTRACT This study evaluated a DNA oligonucleotide array that recognised 38 different Staphylococcus aureus targets, including all relevant resistance determinants and some toxins and species-specific controls. A new method [...]

Microarray studies used for finding genes involved in autoimmune disease

CAMBRIDGE, Mass. (January 21, 2007) — Autoimmune diseases such as type 1 diabetes, lupus and rheumatoid arthritis occur when the immune system fails to regulate itself. But researchers have not known precisely where the molecular breakdowns responsible for such failures occur. Now, a team of scientists from the Whitehead Institute and the Dana-Farber Cancer Institute [...]

Microarray for Clinical Diagnostics- For detecting sepsis

http://www.biologynews.net/archives/2006/12/19/gene_chip_technology_shows_potential_for_identifying_lifethreatening_blood_infection.html Right now there’s no rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital intensive care units. The illness unleashes a powerful inflammatory response that can quickly overwhelm the body, causing organ failure and death, often within days. New research now suggests that doctors one day [...]