Microarrays in Personalized Medicine- $200M-US Aided Personalized Medicine Program

I have written quiet often about this subject and companies that promises solution for personalized medicine. especially the use of genomics information in organ transplant patients and cancer treatment. XDx and Genomic Health are two such companies . XDX has applied microarray, to monitor the immune system, with the help of Gene expression to address [...]

microarray-based Clinical diagnostic tests

 Pathwork Diagnostics, and the Virginia Commonwealth University School of Medicine has initiated an investigational study Genomics-Based diagnostic Test to determine a tumor’s origin so that tissue-specific management can begin. The test uses microarrays from Affymetrix More news on Pathworks website 

A new strain of virus named after Washington University

A new strain of virus has been identified by the medical school and named the “WU” virus after Washington University. The virus, a type known as a polyomavirus, is closely related to two others, JC and BK, which attack the nervous system of HIV patients and cause kidney transplants to fail, respectively. The virus has [...]

The IBM Clinical Genomics for targeted clinical research

THe Haifa Lab of IBM provides the Technlogy for Clinicalgenomics and leads the research in lifesciences fieds. The Clinica, Genomics division plans to provide technology to integrate clinial genomics data and HL7 and other complaince protocls followed in clinical research and clinia, trial and integrate them to provide better and focused clinical trials Clinical genomics [...]

Microarray to detect mutations in largest Human Gene

The average human gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. Residing at Chromosome 4 it has long been of interest to the medical community because its the gene responsible for huntington’s disease, polycystic kidney disease, a form of muscular dystrophy and [...]

Genetics and Business

I have been busy lately but found some time to go through an interesting story and a good article published in scientist magazine Father-in-law of now-infamous extensively drug-resistant TB patient studies tuberculosis at the CDC, and is now under review by the agency Genotyping with PCR -How to choose the right approach I am working on an [...]

Microarray based DRUG DISCOVERY and CLINICAL DIAGNOSIS and biosensor designed to identify viruses

 Prof. David Dandy of Colorado State University chemical and biological engineering has proven that called microarray assays can be used for biomedical disease and drug screening assays could rapidly increase drug discovery, Although not ready for hospital or office use, microarrays represent a novel miniaturized multi-spot diagnostic format that has huge potential for patient diagnosis [...]

‘Personalized Medicine’ Goal of Human Genetics Initiative

Oregon Health & Science University effort, launched 25-April 2007 during National DNA Day, will meld genetics and clinical care OHSU today is launching the Human Genetics Initiative (HGI), an effort that brings together the university’s vast array of genetics research resources and brainpower, and applies them in a health care setting. It will allow the [...]

Theranostics-Genetics Testing for Clinical Diagnostics for Personalized Medicine

Theranostics is the term used to describe the proposed process of diagnostic therapy for individual patients – to test them for possible reaction to taking a new medication and to tailor a treatment for them based on the test results or in plain english Personalized Medicine. Personalized medicine is the use of detailed information about [...]

Defra funds team to build microarray biochip to detect disease outbreaks

A single test for more than 600 deadly viruses is being developed by a group of Defra-funded scientists, offering the possibility of spotting a disease outbreak in hours rather than days. The microarray, which is being led by the Central Science Laboratory near York, with £1.5m funding from Defra, will detect viruses that affect humans, [...]

its not so much of junk DNA- University of Oxford Scientists discoveres Cancer cure with it

 Junk DNA is not junk after all Recently, scientists at the University of Oxford have discovered that ‘junk’ genetic material can switch off cancer tumours, preventing them from growing. By using RNA to switch off a gene involved in controlling cell division, Oxford University scientists may have found a role for RNA in developing new [...]

Microarray based Bio Detection Technologies

DNA microarray detection of antimicrobial resistance genes in diverse bacteria Study published at http://cat.inist.fr/?aModele=afficheN&cpsidt=17459830 High throughput genotyping is essential for studying the spread of multiple antimicrobial resistance. A test oligonucleotide microarray designed to detect 94 antimicrobial resistance genes was constructed and successfully used to identify antimicrobial resistance genes in control strains. The microarray was then [...]

Genetically Guided Treatment For Cancer

Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Researchers developed and validated a new genomic microarray test that identifies whether a [...]

A new twist on DNA-dynamic quality of epigenetics

What makes you different from everyone else on the planet may have less to do with the spelling of your genetic code than with a scattering of chemical “tags” that, like censor’s marks, render some of your genes unreadable.The code itself, after all, is 99.9 percent identical in all of us, so these peripheral elements [...]

NYIT Professor Discovers Next Generation of DNA and RNA Microarrays brings hopes of personalized medicine

A novel invention developed by a scientist from New York Institute of Technology (NYIT) could revolutionize biological and clinical research and may lead to treatments for cancer, AIDS, Alzheimer’s, diabetes, and genetic and infectious diseases. The invention allows the immobilisation of intact. double-stranded, multi-stranded or alternative DNA or RNA and has the potential to revolutionise [...]

Microarray test to anlyse the role of estrogen in breast cancer

Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online. Researchers developed and validated a new genomic microarray test that identifies whether a [...]