Rapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) using OLigonucleotide microarrays

Published by  1Institute for Medical Microbiology and Hygiene, Faculty of Medicine ‘Carl Gustav Carus’, Technical University of Dresden, Dresden and 2Clondiag Chip Technologies GmbH, Jena, Germany ABSTRACT This study evaluated a DNA oligonucleotide array that recognised 38 different Staphylococcus aureus targets, including all relevant resistance determinants and some toxins and species-specific controls. A new method [...]

Microarray studies used for finding genes involved in autoimmune disease

CAMBRIDGE, Mass. (January 21, 2007) — Autoimmune diseases such as type 1 diabetes, lupus and rheumatoid arthritis occur when the immune system fails to regulate itself. But researchers have not known precisely where the molecular breakdowns responsible for such failures occur. Now, a team of scientists from the Whitehead Institute and the Dana-Farber Cancer Institute [...]

Cryptography with DNA binary strands

Biotechnological methods can be used for cryptography. Here two different cryptographic approaches based on DNA binary strands are shown. The rst approach shows how DNA binary strands can be used for steganography to provide rapid encryption and decryption. It is shown that DNA steganogra- phy based on DNA binary strands is secure under the assumption [...]

Microarray for Clinical Diagnostics- For detecting sepsis

http://www.biologynews.net/archives/2006/12/19/gene_chip_technology_shows_potential_for_identifying_lifethreatening_blood_infection.html Right now there’s no rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital intensive care units. The illness unleashes a powerful inflammatory response that can quickly overwhelm the body, causing organ failure and death, often within days. New research now suggests that doctors one day [...]

Carnegie Mellon U. Transforms DNA Microarrays With Standard Internet Communications Protocol

 Source: Carnegie Mellon University December 2005 A standard Internet protocol that checks errors made during email transmissions has now inspired a revolutionary method to transform DNA microarray analysis, a common technology used to understand gene activation. The new method, which blends experiment and computation, strengthens DNA microarray analysis, according to its Carnegie Mellon University inventor, [...]

Bioinformatics Techniques for spam detection

Its not a new topic IBM has discovered that it could use many of the pattern detection techniques and analysis used in bioinformatics in other fields as well. I thought of adding this as bioinformatics is and microarrays are growing in popularity and decided to give few bytes such articles as wel. Many of these [...]

A little bit of fun- I did a PhD and did NOT go mad by Richard Butterworth from university of Middlesex.

I did a PhD and did NOT go mad Before reading these wise words advising you how to do a PhD (inspired by three years of the author carefully and diligently banging his head on a table) you are requested to read and digest the following irony… To say that I enjoyed doing my PhD [...]

Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis: a cohort study

source : http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1555602   Postmenopausal hormone-replacement therapy (HRT) increases breast-cancer risk. The influence of HRT on the biology of the primary tumor, however, is not well understood.   We obtained breast-cancer gene expression profiles using Affymetrix human genome U133A arrays. We examined the relationship between HRT-regulated gene profiles, tumor characteristics, and recurrence-free survival in 72 [...]

DNA Analysis Could Boost Accuracy Of Thyroid Tests

Source: http://www.medicalnewstoday.com/sections/genetics/ By fine-tuning “fine-needle aspiration” biopsies with a super-fast genetic microarray technology, a team of surgeons from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City says they can greatly enhance the accuracy of these tests. “For patients with worrisome thyroid nodules, this means better information on whether the nodule is malignant or benign. [...]

DNA microarray–based analysis may be useful for assessing the risks and benefits of hormone therapy

Hormone-replacement therapy influences gene expression profiles and is associated with breast-cancer prognosis. The US FDa has apprved use of two new microarrays for clinical decision making. The US Food and Drug Administration (FDA) encourages the development of new technologies such as microarrays which may improve and streamline assessments of safety and the effectiveness of medical [...]

Microarrays for Mutation detection and Vaccine development

One of the usage for microarrays could be to study how mutation works in microbes. The work might be helpful in unearthing more details about how bacteria acheive drug resistance. One of the current method is to subject the bacteria to stress (tempareature, drug and other environements) under varying conditions untill it shows resistance to [...]

Microarrays and Toxicogenomics service for Drug development

Microarrays are finding more usage in drug discoverry and development process, toxicogenomics and pharmacogenomics studies have helped researchers to speed up the druug discovery to process, though it is still long way to produce any immediate effect to the patients. The use of toxicogenomics and comparative genomics studies can help scientists to unearth new therapeutic [...]